David W. Lee M.D., FCCP

  • Center Director, Cystic Fibrosis Program, UCSF Fresno
  • Associate Clinical Professor, UCSF
  • Division of Pulmonary, Critical Care and Sleep Medicine, UCSF Fresno

Pulmonary Disease, Critical Care and Sleep Medicine

David W. Lee, M.D., FCCP, is board certified in Internal Medicine, Critical Care Medicine, Pulmonary Disease, and Sleep Medicine.

He earned his medical degree from University of Calgary Faculty of Medicine. His residency in Internal Medicine was completed at University of Massachusetts affiliate hospitals where he served as Chief Resident. His fellowship in Pulmonary and Critical Care Medicine was finished at Alpert Medical School of Brown University.

His professional interests involve the full spectrum of inpatient and outpatient clinical duties in relation to Internal Medicine, Pulmonary, Critical Care and Sleep Medicine. He is a core faculty member in the Internal Medicine Department, Pulmonary and Critical Care Medicine fellowship, and Sleep Medicine fellowship.

Dr. Lee has a special interest in cystic fibrosis. He is the Center Director of the UCSF Fresno Cystic Fibrosis Program for both adult and pediatric care programs. The program has received national accreditation by the Cystic Fibrosis Foundation in 2016 and is an affiliate program of UCSF Medical Center, UCSF Benioff Children’s Hospital, and Children’s Hospital of Oakland programs. All clinics and inpatients are staffed by residents and fellows of the UCSF Fresno residency program. He oversees the care of all pediatric and adult patients and leads, as well as mentors, a multi-disciplinary team of nurses, nutritionists, respiratory therapists, and social workers. In addition, he works closely with the adult program at UCSF Parnassus campus to coordinate lung transplant referrals.

Dr. Lee serves on several influential committees including the Clinical Competency Committee of the UCSF Fresno Pulmonary and Critical Care Medicine fellowship, the Multi Specialty Peer Review Committee of CRMC, the Board of Directors of CCFMG, and the Pediatric Operations Committee at CRMC.

Education and Training

  • University of Calgary Faculty of Medicine, Alberta, Canada; Medical School
  • University of Massachusetts affiliate hospitals; Internal Medicine Residency, Chief Resident
  • Alpert Medical School Of Brown University; Fellowship

Licensure & Certifications

  • California State Medical License
  • American Board of Internal Medicine Certification
  • American Board of Internal Medicine – Critical Care Medicine Certification
  • American Board of Internal Medicine – Pulmonary Disease Certification
  • American Board of Internal Medicine – Sleep Medicine Certification

Research and Publications

  • Ells AL, Kherani A, Lee D. Epiretinal membrane formation is a late manifestation of shaken baby syndrome. J AAPOS. 2003 Jun;7(3):223-5. PMID: 12825067
  • Abu-Hijleh M, Lee D, Braman SS. Tracheobronchopathia osteochondroplastica: a rare large airway disorder. Lung. 2008 Nov-Dec;186(6):353-9. PMID: 18787900
  • Braman S, Lee D. Primary care management of chronic obstructive pulmonary disease: an integrated goal-directed approach. Current Opinion in Pulmonary Medicine 2010. 16(2):83-88. PMID: 20010105
  • Aliotta JM, Pereira M, Johnson KW, de Paz N, Dooner MS, Puente N, Ayala C, Brilliant K, Berz D, Lee D, Ramratnam B, McMillan PN, Hixson DC, Josic D, Quesenberry PJ. Microvesicle entry into marrow cells mediates tissue-specific changes in mRNA by direct delivery of mRNA and induction of transcription. Exp Hematol. 2010 March; 38(3): 233–245. PMID: 20079801
  • Aliotta JM, Lee D, Puente N, Faradyan S, Sears EH, Amaral A, Goldberg L, Dooner MS, Pereira M, Quesenberry PJ. Progenitor/stem cell fate determination: interactive dynamics of cell cycle and microvesicles. Stem Cells Dev. 2012 Jul 1;21(10):1627-38. PMID: 22214238
  • Stanchina ML, Lee D et al. Impact of CPAP use and age on mortality in patients with combined COPD and obstructive sleep apnea: the overlap syndrome. J Clin Sleep Med 2013 Aug 15;9(8):767-72. PMCID: PMC3716667
  • Andrews S, Lee D. Mounier-Kuhn syndrome presenting as cough. Am J Resp Crit Care Med 2014; (189): 1141. PMID: 24787068

Other research activities:

  • Principal investigator for a multi-center controlled study titled “Randomized Trial of Ticagrelor for Severe Community Acquired Pneumonia”
  • Principal investigator for a multi-center SSAIL study in the ICU. Study: Treatment of Septic Shock by inhibiting Auto-digestion and Preserving gut integrity with Enteric LB1148 (SSAIL study)
  • Sub-investigator for APEX study: Acute Medically ill VTE prevention with extended duration Betrixaban Study (APEX)
  • Principal Investigator for Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Assess the Safety, Efficacy, and Tolerability of Tezacaftor/Ivacaftor (TEZ/IVA) in an Orkambi-experienced Population Who Are Homozygous for the F508del-CFTR Mutation

Department Affiliations

UCSF Fresno Department of Internal Medicine